Blakely Lab

The Blakely Lab

Randy Blakely, Ph.D.


Randy Headshot

Allan D. Bass Professor of Pharmacology and Psychiatry

Director, Silvio O. Conte Center for Neuroscience Research

Director, Vanderbilt Postdoctoral Training Program in Neurogenomics

Email: randy.blakely@vanderbilt.edu


THE BLAKELY LAB
at Florida Atlantic University

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Randy D. Blakely, Ph. D.
Executive Director, FAU Brain Institute
Director, Silvio O. Conte Center for Neuroscience Research






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My laboratory explores mechanisms of synaptic regulation, focusing on how clearance of neurotransmitters by presynaptic and glial transporters regulates neurotransmitter signaling capacity. We use molecular biology, transcriptomic and proteomic methods, model system genetics (C. elegans, recombinant inbred mice), molecular and cellular imaging approaches, electrophysiological paradigms, and transgenic mouse approaches to identify mechanisms by which neurotransmitter transporters insure normal synaptic function and how disease risk is impacted by transporter dysfunction. We also seek to understand how drugs, including antidepressants (e.g. SSRIs) and psychostimulants (e.g. cocaine, ADHD medications) carry out their actions. Finally, we seek to understand the web of molecular interactions that act in concert with, or regulate neurotransmitter transporters to insure proper synaptic signaling and plasticity.





Congrats to Gwynne Davis for successfully defending her Neuroscience Ph.D. thesis entitled “Neurobehavioral Impact of Disease-Associated Variation in the Dopamine Transporter” at Vanderbilt University on November 6!

Congrats to Cassie Retzlaff for successfully defending her Neuroscience Ph.D. thesis entitled “Contributions of Metallo-β-Lactamase Domain Containing Protein 1 (MBLAC1) to the Neurobiological Actions of Ceftriaxone” at Vanderbilt University on Nov. 6, 2017



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Congratulations to Matthew Robson for securing an Assistant Professor position at the University of Cincinnati. Matt will be starting up his new lab in January of 2018!


Congratulations to Dr. Adele Stewart for winning one of five travel awards in the postdoctoral fellow category for her talk and poster at the 2017 Brain in Flux Meeting in Maintenon, France.



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Congratulations to Meagen Quinlan for winning one of five travel awards in the graduate category for her talk and poster at the 2017 Brain in Flux Meeting in Maintenon, France.


Silvio O. Conte FAU Brain Institute